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Mature Cystic Teratoma of the Floor of the Mouth

口腔底部成熟囊狀畸胎瘤

摘要


成熟囊狀畸胎瘤(mature cystic teratomas)是一種良性且分化良好的腫瘤,由胚胎原始細胞分化而成,由多於一層胚層之組織而成;好發位置爲性腺體、骶骨與尾骨部或縱隔腔,十分罕見於頭頸部。病理組織學特徵包括:囊狀外層爲角質化鱗狀細胞上皮,包含豐富的汗腺及皮脂腺體,或頭髮與其它真皮附體,及中胚層衍生物如骨骼、軟骨、平滑肌、纖維組織,並可佐以平滑肌特殊染色協助診斷。本院於2006年6月間經歷1名13歲男孩,該病患有氣喘及先天性雙耳聽障經左側人工電子耳植入術病史,此次主訴爲口腔底部無痛膨出腫大病灶約有3個月,大小不會因進食或擠壓而有變化,理學檢查亦無結石或深部硬塊觸及;頭頸部電腦斷層可見一均質囊狀病灶位於口腔底部。手術中顯示病灶爲一具完整平滑表面之水囊狀腫塊,無侵犯下頜腺管道與開口,仔細分離後可完整摘離且保留囊狀外鞘。術後病理診斷爲成熟囊狀畸胎瘤。病患術後於門診追蹤恢復狀況良好。

並列摘要


Benign cystic teratomas are well-differentiated tumors composed of a variety of parenchymal cell types representative of more than one germ layer, usually all three. The most common locations are the gonads and sacrococcygeus. The cavity of the cyst is typically lined with keratinized squamous epithelium and contains abundant sebaceous and sweat glands. Hair and other dermal appendages usually are present. Mesodermal tissue is represented by bone, cartilage, smooth muscle, and fibrous tissue. This report presents a 13-year-old boy with a history of asthma and left cochlear implant insertion due to bilateral congenital sensorineural hearing loss, who came for treatment of a painless bulging lesion on the anterior floor of the mouth noted for 3 months. Computed tomography showed an oval-shaped low-density lesion at the midline of the floor of the mouth without significant enhancement. A tumor with a smooth cystic capsule was completely resected transorally without injury to either the lingual nerve or Wharton's duct. Pathological diagnosis was a mature cystic teratoma. There was no evidence of recurrence to date.

延伸閱讀


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  • 徐允中、吳契璁、許博智、蔣孟達、葉筱雯、林佑俊、李曉屏、陳元武(2012)。下顎單囊造釉母細胞瘤-病例報告臺灣口腔顎面外科學會雜誌23(1),45-54。https://doi.org/10.7104/TJOMS.201203.0046
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