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摘要


藥物性鼻炎屬於非過敏性鼻炎的一類,因爲特定藥物的使用而引發或是加重鼻炎症狀,且可能合併出現在有過敏性或其他非過敏性鼻炎的病患。目前有關藥物性鼻炎的確切致病機轉依然不明,有學者依照可能的原理將它分爲三類,包括局部務炎性、神經性以及特發性:rhinitis medicamentosa則是具有特殊性的一種藥物性鼻炎,和長期不當使用局部鼻血管收縮劑有關。停止服用相關藥物和逐漸降低局部鼻血管收縮劑的使用是治療的首要方式,必要時可以使用類固醇鼻噴劑或是合併鼻內抗組織胺來緩解症狀。

並列摘要


Drug-induced rhinitis is a type of non-allergic rhinitis, referring to a clinical spectrum of the development or exacerbation of rhinitis related to the use of certain medications. Three categories of drug-induced rhinitis have been proposed based on the mechanism of action. These include local inflammatory, neurogenic and idiopathic types. Rhinitis medicamentosa, a form of drug-induced rhinitis, has unique characteristics and is related to inappropriate use of topical decongestants. When possible, the offending medication should be discontinued or substituted in terms of management. Although there are no established treatment recommendations for drug-induced rhinitis other than avoidance, clinical experience suggests that it would be reasonable to initiate use of an intranasal corticosteroid spray to treat symptomatically. The addition of an intranasal antihistamine in combination with use of an intranasal corticosteroid may be considered as step-up therapy if the intranasal corticosteroid alone is not effective.

延伸閱讀


  • 樹金忠、王鶴健(2009)。藥物性肺炎當代醫學(424),87-88。https://doi.org/10.29941/MT.200902.0003
  • 李健源、方深毅(2007)。慢性難治性鼻竇炎台灣耳鼻喉頭頸外科雜誌42(),101-111。https://doi.org/10.6286/2007.42.s_1.101
  • 徐茂銘(1977)。慢性鼻竇炎當代醫學(46),729-730。https://doi.org/10.29941/MT.197708.0006
  • 黃得韻、戴志展(2011)。Epidemiology of Rhinitis台灣耳鼻喉頭頸外科雜誌46(s_1),4-7。https://doi.org/10.6286/2011.46.s_1.4
  • Warren, T. B., Warren, D. P., & Soper, D. E. (1998). Upper Respiratory Infections--Allergic Rhinitis. Infectious Diseases in Obstetrics and Gynecology, 1998(), 48-48. https://doi.org/10.1155/S1064744998000118

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