原發性陣發性運動失調

Primary Episodic Ataxia

陳建志(Jiann-Jy Chen) ； 陳登郎(Dem-Lion Chen)

《台灣耳鼻喉頭頸外科雜誌》 51卷4期 (2016/12) Pp. 249-253

https://doi.org/10.6286/2016.51.4.249

摘要

一37歲女性，每隔大約3年就會發作1次眩暈，發作時還會出現持續性地輕度頭痛，每次發作會持續個大約1週。某次發作求診於本院，理學檢查顯示注視性眼振及小腦性運動失調，神經影像、血液學及尿液學檢查均無異常發現，診斷為原發性陣發性運動失調，在投予口服acetazolamide後，病情迅速緩解。原發性陣發性運動失調臨床上並不多見，是一種相當良性的疾病。雖然也會眩暈發作，根據小腦性運動失調的症狀，可跟一般常見的週邊性眩暈區別，而治療策略亦大相逕庭；不僅如此，也必需跟腦幹預兆偏頭痛和椎基底動脈循環不全分別。

關鍵字

episodic ataxia ； nystagmus ； cerebellar signs ； vertigo（陣發性運動失調 ； 眼振 ； 小腦徵候 ； 眩暈）

並列摘要

A 37-year-old woman has been bothered with vertiginous episode every three years. During symptomatic, she mildly felt headachy. Then, vertigo and headache would persist for about one week. During one episode, she visited our clinic. Physical examination demonstrated gaze nystagmus and cerebellar ataxia. Neuroimagings, blood and urine examinations reported unremarkable. After acetazolamide has been prescribed orally, the symptoms subsided dramatically. Primary episodic ataxia was uncommon clinically, and is a quite benign disease. Despite vertigo, it presents with cerebellar ataxia, which differs from common peripheral vertiginous diseases; hence, its therapy differs, too. Furthermore, it should be differentiated from migraine with brainstem aura and vertebrobasilar insufficiency.

並列關鍵字

episodic ataxia ； nystagmus ； cerebellar signs ； vertigo