人類乳突瘤病毒－從子宮頸癌到頭頸癌

Human Papillomavirus-from Cervical Cancer to Head and Neck Cancer

廖立人(Li-Jen Liao) ； 婁培人(Pei-Jen Lou)

《台灣耳鼻喉頭頸外科雜誌》 56卷2期 (2021/06) Pp. 70-77

https://doi.org/10.6286/jtohns.202106_56(2).070

摘要

隨著政府宣導抽菸、嚼食檳榔與口腔癌發生的相關危險性，以提升民眾對頭頸癌的重視，並藉由提高菸稅與口腔黏膜篩檢等活動推行，台灣頭頸癌的發生率於2014年達到高峰，之後開始呈現逐年下降的趨勢。相反的，人類乳突瘤病毒（human papillomavirus, HPV）相關的口咽癌發生率卻反而上升，因此本議題顯得更形重要。本文回顧人類乳突瘤病毒在子宮頸癌的防治狀況，以及整理近年來台灣耳鼻喉頭頸腫瘤學界對於人類乳突瘤病毒與頭頸癌的相關研究，同時展望未來耳鼻喉頭頸腫瘤外科面對人類乳突瘤病毒需要關注之事項。

關鍵字

head and neck cancer ； human papillomavirus ； oropharyngeal cancer（頭頸癌 ； 人類乳突瘤病毒 ； 口咽癌）

並列摘要

With the increasing awareness of the risk of smoking and betel nut chewing for head and neck cancer, as well as increased tobacco taxes and oral mucosa screening activity, the incidence of head and neck cancer in Taiwan reached its peak in 2014 and then began to decrease every year. However, the incidence of oropharyngeal cancer related to human papillomavirus (HPV) has increased; therefore, this issue is even more important. This article reviews the current status of human papillomavirus prevention and treatment in cervical cancer, summarizes the research on HPV-related head and neck cancer in Taiwan in recent years, and provides a future perspective on HPV in head and neck cancer.

並列關鍵字

head and neck cancer ； human papillomavirus ； oropharyngeal cancer