The European Integration (EI) has enlarged five times since 1958; the member states numbers are from six to twenty-seven. This sixth enlargement for EI is not only strengthening the deepening but widening toward to 21st century. In the period of Post-Cold War, regional integration is one of the most important trends of international politics; European Integration is the most successful example at present. This paper tries to observe EI, the spatial change factor and spatial change trend, and objectively analyses the background, incentives, process and pattern of EI enlargement. It is also expected to stimulate extensive and in-depth understanding on EI and European area, as well as provide a research skeleton on the spatial governance strategy of the future European Integration.