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乾眼症之結膜細菌菌落

The Bacterial Flora of Conjunctiva in Dry Eye Disorders

摘要


連續選取24例(48眼)嚴重乾眼症患者,其中15例為乾性角結膜炎(Keratoconjunctivitis sicca),9例為Stevens-Jonhson氏症候群。結膜細菌培養結果顯示,陽性培養率與正常結膜或慢性結膜炎患者大致相似,但乾眼症結膜菌落却有高比率之混合性感染,菌種也以革蘭氏陰性菌所占比率最高,其中更以毒性強之綠膿桿菌屬為最多,所培養出的茵種對一般所使用的抗生素均呈高比率之抗藥性。所以高危險群乾眼症患者應慎選抗生素以作預防性治療。

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並列摘要


The conjunctival bacterial cultures were done in twenty-four consecutive patients (48 eyes) who suffered from severe dry eye disorders. There were 15 patients with keratoconjunctivitis sicca and 9 with Stevens-Johnson syndrome. The rate of positive conjunctival bacterial culture showed no significant difference among the normal conjunctival group (51.8%) chronic conjunctivitis (43.5%), and dry eye disorders (54.2%). However, in dry eye disorders the higher mixed culture rate (46.2%) and Gram negative bacteria predominant were found. All cultured strains showed relatively antibiotics resistance. Cautious should be taken to use antibiotics as prophylactic treatment to dry eye patients.

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