多發性曇花一現性眼底白點症候羣

Multiple Evanescent White-Dot Syndrome

張由美(Yu-Mei Chung) ； 葉則祥(Tse-Shiang Yeh) ； 劉榮宏(Jorn-Hon Liu)

《中華民國眼科醫學會會刊》 27卷2期 (1988/05) Pp. 958-963

https://doi.org/10.30048/ACTASOS.198805.0168

摘要

提出兩例中國女性之多發性曇花一現性眼底白點症候群(multiple evanescent white-dot syndrome)病例報告。
病例1為18歲女性患者，主訴右眼視力減退。右眼眼學檢查發現玻璃體細胞1度、網膜中央小凹顆粒狀變化(foveal granularity)及從黃斑部周邊(perimacula)到赤道部(equator)的深層網膜及色素上皮細胞層可見境界分明的小白點。螢光血管攝影早期可見點狀的過螢光而晚期可見網膜色素細胞層的螢光染色。網膜電圖及眼電圖比率都呈低下。左眼則正常。病人右眼視力於6星期後恢復而眼病變也完全消失。在1年的追踪檢查中，未見有復發現象。病例2為17歲女性，主訴右眼視力減退。眼部檢查可見玻璃體細胞1度、網膜中央小凹顆粒狀變化及眼底從黃斑部周邊到赤道部散在性白斑。眼底螢光血管攝影除有類似病例1的變化外，可見視乳頭及其周圍網膜靜脈有螢光漏出(fluorescein dye leakage)。左眼則正常。這些右眼病變於5星期內消失，視力也恢復正常。
兩例均符合Jampol等人於1984年提出報告的多發性曇花一現性白點症候群(multiple evanescent white-dot syndrome)。

並列摘要

Two Chinese females, aged 17 and 18 years respectively, suffered from acute visual loss in the right eye. In both cases, there were 1+ vitreous cells, foveal granularity and small discrete white dots in the. fundus. The white dots appeared at the level of the retinal pigment epithelium or deep retina and spreaded from perimacula to equator. Early phase angiograms showed multiple punctate areas of hyperfluorescence and late phase showed more diffuse pattern of staining of retinal pigment epithelium. Fluorescein dye leakage from optic disc and peripapillary retinal veins in one and depressed electro-retinography and electro-oculography ratio iii the other case were noted. The left eye was normal. The visual acuity recovered along with disappearance of all ocular lesions within 6 weeks in both cases. The clinical picture in these two cases conforms to the multiple evanescent white-dot syndrome which was first proposed by Jampol et al in 1984. No recurrence or involvement of the left eye was noted during a follow-up of 1 year in one case. The other case was lost of follow-up.

並列關鍵字

multiple evanescent white-dot syndrome ； retinal pigment epithelium disease ； Chinese patients