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VKH症候群之臨床觀察
Clinical Observation of VKH Syndrome
摘要
Vogt-Koyanagi-Harada症候群是一種以黑色素細胞為攻擊目標的自體免疫異常疾病。主要侵犯葡萄膜、內耳、皮膚毛髮及腦膜，造成各種不同程度的症狀。由於此病可同時侵犯葡萄膜及腦膜，因此也有人稱之為uveomeningitic Syndrome。 台中榮總近四年來共有16例VKH症候群之病例，本篇就其臨床症狀、治療方式及併發症予以探討。
關鍵字
無資料並列摘要
A series of 16 consecutive cases of Vogt-Koyanagi-Harada syndrome were studied clinically. There were 7 males and 9 females, aged from 18 to 53 years with an average of 34 years. All the patients were referred with the chief complaint of ”rapid loss of vision”. Neurological manifestations, such as vertigo, headache, nausea, vomiting, tinnitus, hearing defect, ataxia and neck stiffness, were the initial symptoms of VKH syndrome. Ophthalmic manifestations included exudative retinal detachment, Dalen-Fuchs nodule, hyperemic & swollen disc, iridocyclitis and vitreous cell. Alopecia, poliosis and vitiligo were the convalescent manifestations. In the late stage, sunset glow fundus, chronic anterior uveitis, glaucoma and cataract were found. They were treated with large dose corticosteroids, and good recovery of visual acuity was achieved, only 3 cases suffered from recurrence. Two cases failed due to inadequate corticosteroids therapy.
延伸閱讀
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