Phenylephrine試驗在眼瞼下垂患者的應用

Phenylephrine Test and Ptosis

馬俐(Lih Ma) ； 高錦弘(Ching-Hong Kao)

《中華民國眼科醫學會雜誌》 31卷1期 (1992/03) Pp. 41-49

https://doi.org/10.30048/ACTASOS.199203.0009

摘要

10% phenylephrine was instilled into 97 patients to observe its pharmacological action on the eyelids. Phenylephrine is primarily a sympathomimetic agent. It causes direct stimulation at the muscle receptor site. It haas been reported to elevate the upper 2-3 mm in some ptosis patients.
Patients were divided into 17 groups including:
1. Normal subjects, 11 eyes
2. Congenital ptosis, 13 eyes
3. Senile ptosis, 26 eyes
4. Myasthenia Gravis, 3 eyes
5, Ptosis following CL. wearing, 6 eyes
6. Plods following CVA attack, I eye
7. Acquired Homer's syndrome, 2 eyes
8. Ptosis following cataract extraction, 3 eyes
9. Ptosis following pterygium excision, I eye
10. Trauma, 2 eyes
11. Acquired ptosis (cause unknown), 4 eyes
12. Pseudoptosis, 3 eyes
13. Graves' lid retraction, 8 eyes
14. Following levator resection operation, 5 eyes
15. Following levator recession operation, 2 eyes
16. Following Mullerectomy, 2 eyes
17. Following trauma and frontalis sling, I eye
Almost all of the patients, except in group 10, 13, response to phenylephrine.
The mean changes of vertical palpebral fissure to 17 groups ranged from-0.2 mm to 2.67 mm, Its group 2, 10, 13, 14, 17, the mean elevations were less than 1.0 mm. In group 1, 4, 6, 7, 11, 15, 16, the mean elevations were between 1.0 mm and 2.5 mm. In group 3, 5, 8, 9, 12 the nsean elevations were greater titan 2.5 mm,
The purpose of this study are (1) defuse the mechanism of the ptosis, whether the ptosis is induced by weakening of the levator muscle or Müller's muscle. (2) determine preoperatively the effect of epinephrine containing anesthetic solutions on the lid, and avoid the epinephrine in the mixture if the response of the lid higher than 2.5 mm.

並列摘要

10% phenylephrine was instilled into 97 patients to observe its pharmacological action on the eyelids. Phenylephrine is primarily a sympathomimetic agent. It causes direct stimulation at the muscle receptor site. It haas been reported to elevate the upper 2-3 mm in some ptosis patients.
Patients were divided into 17 groups including:
1. Normal subjects, 11 eyes
2. Congenital ptosis, 13 eyes
3. Senile ptosis, 26 eyes
4. Myasthenia Gravis, 3 eyes
5, Ptosis following CL. wearing, 6 eyes
6. Plods following CVA attack, I eye
7. Acquired Homer's syndrome, 2 eyes
8. Ptosis following cataract extraction, 3 eyes
9. Ptosis following pterygium excision, I eye
10. Trauma, 2 eyes
11. Acquired ptosis (cause unknown), 4 eyes
12. Pseudoptosis, 3 eyes
13. Graves' lid retraction, 8 eyes
14. Following levator resection operation, 5 eyes
15. Following levator recession operation, 2 eyes
16. Following Mullerectomy, 2 eyes
17. Following trauma and frontalis sling, I eye
Almost all of the patients, except in group 10, 13, response to phenylephrine.
The mean changes of vertical palpebral fissure to 17 groups ranged from-0.2 mm to 2.67 mm, Its group 2, 10, 13, 14, 17, the mean elevations were less than 1.0 mm. In group 1, 4, 6, 7, 11, 15, 16, the mean elevations were between 1.0 mm and 2.5 mm. In group 3, 5, 8, 9, 12 the nsean elevations were greater titan 2.5 mm,
The purpose of this study are (1) defuse the mechanism of the ptosis, whether the ptosis is induced by weakening of the levator muscle or Müller's muscle. (2) determine preoperatively the effect of epinephrine containing anesthetic solutions on the lid, and avoid the epinephrine in the mixture if the response of the lid higher than 2.5 mm.

並列關鍵字

phenylephrine test ； ptosis ； Müller's muscle