低張及高張靜脈輸注液對玻璃體出血之治療

The Treatment of Vitreous Hemorrhage Using Intravenous Infusion Therapy with Hypotonic and Hypertonic Fluid

李尚儒(Shang-Ju Lee) ； 呂忠苓(Chong-Lin Lue) ； 蔡武甫(Wu-Fu Tsai)

《中華民國眼科醫學會雜誌》 33卷2期 (1994/06) Pp. 217-223

https://doi.org/10.30048/ACTASOS.199406.0012

摘要

由1991年6月至1992年10共收集42例玻璃體出血病患：31例為糖尿病視網膜症，2例為急性後玻璃體膜剝離，3例為眼球鈍挫傷，5例為網膜側枝靜脈阻塞，另1例為老年性黃斑變性。42例中男性27位、女性15位。年齡分佈向16歲至73歲。每位病人每天都給予低張液(0.45%Nacl)500ml及高張液(Manitol)劑量每公斤體重1.5公克之20%溶液各壹次靜脈全速注射，療程共一星期。另外以回溯性方式自1989年7月至1990年12月由病歷資料找出患有玻璃體出血，同時只接受門診追蹤檢查的病例共32位，追蹤期為3至12個月，分析其玻璃體出血吸收情形，以與治療組作對照比較。結果治療組42例中有25例(59.5%)在治療後第3到第5天玻璃體出血明顯轉清晰，同時視力也有進步。而對照組32例中玻璃體自然吸收者有7例(21.8%)。統計上二組的差異有意義。

並列摘要

We used a simple, nonsurgical method to treat 42 eyes in 42 patients with vitreous hemorrhage secondary to various vitreoretinal disorders. In every patient, hypotonic solution (0.45% NaCl) and hypertonic solution (maintol) intravenous infusion had been given every day. The amount of fluid infused in each day was: hypotonic solution 500ml and 20% hypertonic solution (7.5ml/kg B.W.). Hypotonic solution was given first, then hypertonic solution was infused five hours later. Duration of treatment was one week. The vitreous hemorrhage cleared and visual acuity improved in 25 eyes (59.5%). For control study, the data of 32 eyes of vitreous hemorrhage without any treatment were reviewed. In 3 to 12 months of observation period, vitreous hemorrhage spontaneously cleared in 7 eyes (21.8%). The difference between the results of treatmnet group and control group was statistically significant. (p=0.002, CHI-SQUARE)

並列關鍵字

Vitreous hemorrhage ； Hypertonic solution ； Hypotonic solution