The study collects 83 POAG patients and 37 glaucoma suspect patients using Volk double aspheric lens 90D or transequator lens to inspect the types of nerve fiber layer defects. Most glaucoma patients (45.9%) have diffuse atrophy. Only 9.5% of the glaucoma suspect patients have abnormal nerve fiber layer defects, of which all are slit defects. Forty-nine percent of patients with diffuse atrophy have moderate or severe VF defect. Sixty-one percent of patients with wedge-shaped defect have mild VF defect. The correlation with Octopus G1 VF indices indicates that the MD of diffuse atrophy is significantly higher than the MD of wedge-shaped defect (p<0.05). There is no statistically significant difference in CLV (p>0.05) between the patients with wedge-shaped defect and those with diffuse atrophy. The types of nerve fiber layer defects are highly correlated with the severity of VF defect and VF indices (MD, CLV). It can serve as an important supplement means to detect glaucoma in its early stage.
The study collects 83 POAG patients and 37 glaucoma suspect patients using Volk double aspheric lens 90D or transequator lens to inspect the types of nerve fiber layer defects. Most glaucoma patients (45.9%) have diffuse atrophy. Only 9.5% of the glaucoma suspect patients have abnormal nerve fiber layer defects, of which all are slit defects. Forty-nine percent of patients with diffuse atrophy have moderate or severe VF defect. Sixty-one percent of patients with wedge-shaped defect have mild VF defect. The correlation with Octopus G1 VF indices indicates that the MD of diffuse atrophy is significantly higher than the MD of wedge-shaped defect (p<0.05). There is no statistically significant difference in CLV (p>0.05) between the patients with wedge-shaped defect and those with diffuse atrophy. The types of nerve fiber layer defects are highly correlated with the severity of VF defect and VF indices (MD, CLV). It can serve as an important supplement means to detect glaucoma in its early stage.