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Dacryocystitis: Microbiology and Drug Susceptibility

淚囊炎:微生物和藥物敏感性之研究

摘要


目的:測定導致淚囊炎的致病菌種和對其有效的抗生素。 方法:回顧性的收集由民國84年4月到民國87年6月淚囊炎的致病菌種和其抗生素敏感性試驗的結果。 結果:由28個檢體培養出20株致病菌種。陽性培養率為60.7%,革蘭氏陰性菌最多佔45%,其中以Klebsiella pneumoniae.為主。革蘭氏陽性菌佔30%,其中以Staphylococcus aureus為主。厭氧菌佔10%,而黴菌佔15%。幾乎所有培養出的需氧菌的抗生素試驗對piperacillin, amikacin, vacomycin, ciprofloxacin, ofloxacin, norfloxacin都呈現敏感反應,厭氧菌對piperacillin和chloram-pheicol均成敏感。 結論:台灣南部的淚囊炎的微生物學和其藥物敏感姓試驗的本土資料可作為選擇抗生素的初步依據。

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並列摘要


Purpose: To determine the current spectrum and antimicrobial aspect of pathogens causing dacryocystitis. Method: Retrospective study of microbiologic records and results of antimicrobial susceptibility tests collected between April 1995 to June 1998. Result: Twenty isolates of pathogens were cultured from 28 samples of dacryocystitis. The positive culture rate was 60.7%. Gram-negative aerobes (45% of the isolates) were most common in dacryocystitis pathogens and the predominant bacteria was Klebsiella pneumoniae. Gram-positive aerobes were present in 30% of dacryocystitis pathogens, and the predominant one was Staphylococcus aureus. Anaerobic bacteria were isolated in 10%, and fungus was found in 15%. Most of aerobic bacteria were susceptible to piperacillin, amikacin, vancomycin, ciprofloxacin, ofloxacin, and norfioxacin. Anaerobes were susceptible to piperacillin and chloramphenicol. Conclusion: The native data of microbiology and antimicrobial aspect of dacryocystitis in southern Taiwan could be a preliminary reference of optimizing the antibiotic therapy.

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