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年輕人的中心視網膜靜脈阻塞

Central Retinal Vein Occlusion in Young

摘要


目的:年輕人的中心視網膜靜脈阻塞比較少見,而且在臨床特徵,致病機轉以及視力預後等方面和老年人常有所不同。本篇針對年輕人的中心視網膜靜脈阻塞(CRVO in young),來做血液篩檢及評估其臨床特性。 方法:本篇以回溯性分析整理,從1984年至1997年十三年間,在台中榮總診斷為中心視網膜靜脈阻塞,且發生年齡在50歲以下之病人共17位,來調查其臨床特性,並做血液黏稠度以及凝血因子篩檢。 結果:年輕型中心視網膜靜脈阻塞約占全部中心視網膜靜脈阻塞的1.2%,伴隨有全身性疾病的比例為47%。年輕型13位接受血液篩檢的病人,全血黏稠度平均6.14,血漿黏稠度平均2.76,校正後血液黏稠度4.26,而對照組13位老年型病人的三項平約值分別為5.74、2.12、3.35。二組之結果均比正常人高,二組中均無發現具有活化蛋白質C的抗性。 結論:血液篩檢方面,在全血液黏稠度及血漿黏稠度二項,所有中心視網膜靜脈阻塞的患者均偏高,而且未發現中心視網膜靜脈阻塞患者當中具有活化蛋白質C之抗性者。

關鍵字

無資料

並列摘要


Purpose: CRVO in young adults is different from that in elderly. This study evaluated the clinical characteristics, blood coagulation function and viscosity state of CRVO in young. Methods: A retrospective study, from 1984 to 1997, to evaluate the age, systemic associations, treatments, initial and final visual acuity, and collect blood sample for viscosity and coagulation tests. Results: The incidence of CRVO in young is 11.2% in all CRVO. The systemic association of young CRVO is 47%. The mean whole blood viscosity (WBV) in young is 6.14, plasma viscosity (PV) is 2.76, corrected blood viscosity (CBV) is 4.26. In elderly group, the WBV is 5.74, PV is 2.12, and CBV is 3.35. Conclusion: CRVO in both young and elderly group had elevated whole blood viscosity and plasma viscosity than normal people. No finding of activated protein C resistance in CRVO, neither in young nor elderly group in this study.

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