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Clinical and Oct Characteristics of Peripapillary Detachment in Pathologic Myopia

病理性近視繼發視盤周圍網膜剝離之臨床及光學共軛掃描儀下特徵

摘要


目的:研究病理性近視繼發視盤周圍網膜剝離在臨床與光學共軛掃描儀下的特徵。 方法:共收集自2006年l月至2009年2月問病理性近視繼發視盤周圍網膜剝離的案例,將每位病人的性別、年齡、最佳矯正視力、屈光度、眼軸長、眼底檢查及光學共軛掃描儀結果做資料分析。 結果:共計60位病人(90個眼睛)列入資料分析,包括39位女性及21位男性,平均年齡為45.9歲,平均最佳矯正視力為0.77,平均屆光度為-11.14D,平均眼軸長為28.13 mm,其中39個眼睛在間接眼底檢查下可發現典型的病理性近視繼發視盤周圍網膜剝離特徵,在視盤周圍有一黃橘色、局部、邊界清楚的病灶,其中在13個眼睛發現有視盤小凹狀構造,佔14.4%,此構造連接玻璃體與視網膜色素層下方的空腔。 結論:利用光學共軛掃描儀研究發現並非所有病理性近視繼發視盤周圍網膜剝離的眼睛皆顯示典型的視盤周圍橘黃色病灶,雖然目前病理性近視繼發視盤周圍網膜剝離的病理機制仍不清楚,但我們認為視盤小凹狀構造對病理性近視繼發視盤周圍網膜剝離的形成扮演一定的角色。

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並列摘要


Purpose: To investigate the clinical and OCT characteristics of peripapillary detachment in pathologic myopia (PDPM). Methods: Medical records of patients with PDPM diagnosed from January 2006 to February 2009 were reviewed. Data analysis included sex, age, best-corrected visual acuity (BCVA), refractive error, axial length, fundoscopic and OCT findings. Results: 60 patients (90 eyes) were analyzed. There were 39 females and 21 males in this study. The mean age was 45.9±10.8 years and the mean BCVA in log MAR was 0.77±0.36. The mean refractive error in spherical equivalent (SE) was the -11.14±4.04 D and mean axial length (AL) was 28.13±1.69 mm. Indirect ophthalmoscopy revealed the presence of a typical yellow-orange, localized, well-circumscribed peripapillary lesion in 39 (43.3%) eyes with PDPM. Communication between the vitreous cavity and sub-RPE space through pit-like structure was demonstrated in 13 of 90 eyes (14.4%). Conclusion: The presence of a typical yellow-orange peripapillary retinal lesion might not be an evident fundoscopic feature for all eyes with demonstrable PDPM by optical coherence tomography. Although its pathogenesis and pathologic significance require further investigation, the peripapillary pit-like structure may play a role in the formation of PDPM.

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