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Intravitreal Bevacizumab Therapy for the Treatment of Choroidal Neovascularization Secondary to Angioid Streaks: A Case Report
以玻璃體內注射癌思停治療類血管狀破裂症併脈絡膜新生血管：病例報告
摘要
目的：報告一例類血管狀破裂症併脈絡膜新生血管以玻璃體內注射癌思停治療的案例。方法：病例報告。結果：一位53歲男性在六年前左眼因類血管狀破裂能併黃斑部脈絡膜新生血管而接受雷射治療，之後黃斑部結疤使左眼視力僅有20／1000。三年前，原本視力較好的右眼也變模糊，視力從20／33降到20／400，螢光血管造影檢查發現右眼黃斑部有來自於脈絡膜新生血管的活動性滲漏點，網膜斷層掃擋車顯示右眼黃斑部有視網膜下積液，而左眼黃斑部結疤並無活動性滲漏點。之後右眼開始接受玻璃體內注射癌思停治療，治療後黃斑部視網膜下積液減少，病人視力改善，追蹤三年共注射八次，目前視力右眼20／40而左眼仍是20／1000。結論：玻璃體內注射癌思停治療可抑止類血管狀破裂症併脈絡膜新生血管，並幫助改善病人視力。
關鍵字
無資料並列摘要
Purpose: To report a case of choroidal neovascularization (CNV) secondary to angioid streaks that was treated using intravitreal bevacizumab (IVB) injections.Methods: Case report.Results: A 53-year-old man had undergone focal laser photocoagulation for juxtafoveal CNV in his left eye 6 years ago. The macular lesion developed into a scar, and the best-corrected visual acuity (BCVA) of his left eye remained at 20/ 1000 thereafter. However, 3 years ago, he developed blurred vision in his previously CNV-free right eye. The BCVA of his right eye decreased from 20/33 to 20/ 400. Fundus examination showed peripapillary angioid streaks in both eyes, macular CNV with submacular hemorrhages in the right eye, and pigmented macular scars with salmon patches in the left eye. Fluorescein angiography showed active dye leakage from a subfoveal CNV in the right eye. Optical coherence tomography examination showing retinal lesion with subretinal fluid (SRF) further confirmed the diagnosis of CNV. IVB (1.25 mg/0.05 ml) was then injected in his right eye. After IVB injections, the BCVA improved and SRF resolved. During the 3-year follow-up period, the patient received a total of 8 IVB injections in the right eye. At the last follow-up, the BCVA of the right eye and left eye was 20/40 and 20/1000, respectively.Conclusion: Intravitreal injected bevacizumab seems to have a therapeutic effect in that it stabilizes visual acuity and suppresses CNV secondary to angioid streaks.
延伸閱讀
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