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Preliminary Report on Effect of Selective Laser Trabeculoplasty (SLT) in Treatment of Open-Angle Glaucoma

以選擇性雷射小樑網整形術治療隅角開放性青光眼之報告

摘要


Purpose: To report the intraocular pressure (IOP) reduction following selective laser trabeculoplasty (SLT) in open angle glaucoma (OAG).Method: A retrospective, nonrandomized, interventional case series was carried out. Consecutive OAG patients underwent SLT; the same preoperative medical regimen was maintained during follow-up. Data collected included age, gender, phakic or pseudophakic eye, laser power and number of laser spots, previous surgery, pre- and postoperative IOP, number of glaucoma medications, and surgical complications. Post-treatment assessments were scheduled at 1 week and month 1, 2, 3, 4, 5, and 6.Results: A total of twenty eight patients with fifty six eyes were enrolled. We found the average prelaser IOP was 21.3±3.7 mmHg and the average postlaser IOP was 17.2±3.7 mmHg at sixth months. The mean IOP reduction is 3.5 mmHg (P<0.05) at last visit. Successful treatment was defined as IOP reduction more than 20% or at least one kind of anti-glaucomatic agent withdrawal. Overall success rate was 40%. No major complication was found.Conclusions: Our study showed that SLT could provide a safe and effecttive outcome in treating OAG patients. Pre-laser IOP is positively correlated with IOP reduction. (P<0.05).

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並列摘要


Purpose: To report the intraocular pressure (IOP) reduction following selective laser trabeculoplasty (SLT) in open angle glaucoma (OAG).Method: A retrospective, nonrandomized, interventional case series was carried out. Consecutive OAG patients underwent SLT; the same preoperative medical regimen was maintained during follow-up. Data collected included age, gender, phakic or pseudophakic eye, laser power and number of laser spots, previous surgery, pre- and postoperative IOP, number of glaucoma medications, and surgical complications. Post-treatment assessments were scheduled at 1 week and month 1, 2, 3, 4, 5, and 6.Results: A total of twenty eight patients with fifty six eyes were enrolled. We found the average prelaser IOP was 21.3±3.7 mmHg and the average postlaser IOP was 17.2±3.7 mmHg at sixth months. The mean IOP reduction is 3.5 mmHg (P<0.05) at last visit. Successful treatment was defined as IOP reduction more than 20% or at least one kind of anti-glaucomatic agent withdrawal. Overall success rate was 40%. No major complication was found.Conclusions: Our study showed that SLT could provide a safe and effecttive outcome in treating OAG patients. Pre-laser IOP is positively correlated with IOP reduction. (P<0.05).

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