It has been 7 years since the Centers for Disease Control completed its take over of all anti-tuberculosis programs. From the over-emphasis on the reporting of suspected cases, at the same time, overlooking the diagnostic quality and tuberculosis case-management in its early phase, to the implementation of directly observed therapy-short course (DOTS) programs and the establishment of multidrug resistant treatment teams in recent years, CDC seems gradually stepping into the right direction by fostering close cooperation between clinical and public health aspects of tuberculosis care. This article briefly reviews the evolution of organizational manpower, TB patient registries, case detection, and drug resistant tuberculosis management. I hope that through this review, we can all look forward to stable, continuous growth of the anti-tuberculosis efforts, removing all obstacles those block patients from reaching medical care, fighting against tuberculosis side by side with TB patients.