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Determination of Phenylpropanolamine in Pharmaceutical Preparations by Second Derivative Spectrophotometry

並列摘要


Phenylpropanolamine (PPA) hydrochloride used as nasal decongestant agent was determined by second derivative spectrophotometry after derivatization with 2-hydroxynaphthaldehyde. The absorbance was measured between minimum-maximum of 386nm-392nm. The linear calibration range was obtained within 0.5~2.0μg/mL. The method was applied for the determination of phenylpropanolamine from pharmaceutical preparations Tavegyl-D and Sinutab with coefficient of variation of 0.8~1.6%. Paracetamol present together with phenylpropanolamine could also be determined by spectrophotometry in aqueous phase after extraction of PPA in chloroform.

被引用紀錄


陳婉君(2012)。製備CdS-Chi/Gel、MWCNT及PLC/AuNPs修飾電極偵測DNA鹼基、 藥物與大腸桿菌〔碩士論文,國立臺北科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0006-0108201201182600

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