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Assessment of Methamphetamine Abuse Patterns in Southern Taiwan by Immunoassay and Quantification by Gas Chromatographic-Mass Spectrometric Analysis of Urine Samples

利用免疫分析法與氣相層析質譜分析法分析台灣南部地區甲基安非他命濫用情形之研究

摘要


在台灣,甲基安非他命是一個重要的濫用藥物。本研究於2006年7月至2006年12月,分別收集嘉義市、嘉義縣、台南市、台南縣、高雄市、高雄縣和屏東縣等台灣南部地區七縣市之列管毒品人口尿液檢體,共有5452個尿液檢體,並利用免疫分析法進行初步檢驗與氣相層析質譜分析法進行確認檢驗,分析台灣南部地區甲基安非他命之濫用情形。研究結果顯示,台灣南部地區甲基安非他命的陽性率和濃度分別爲10.9±2.3%和16535±5682ng/mL。台灣南部地區甲基安非他命的陽性率以台南市爲最高(14.4%),其次依序爲嘉義市(13.2%)、屏東縣(11.3%)、高雄縣(11.2%)、嘉義縣(9.0%)、台南縣(8.7%)、高雄市(8.7%)。而台灣南部地區甲基安非他命的平均濃度亦以台南市爲最高(23892 ng/mL),其次依序爲台南縣(20566 ng/mL)、嘉義縣(17877 ng/mL)、高雄縣(17750 ng/mL)、屏東縣(16260 ng/mL)、高雄市(13343 ng/mL)、嘉義市(6058 ng/mL)。

並列摘要


Methamphetamine (MA) is one of the most commonly abused drugs in Taiwan. In order to investigate the abuse patterns of MA in the Southern Taiwan, urine samples were collected from specified residents of Chiayi City (CCI), Chiayi county (CCO), Tainan City (TCI), Tainan County (TCO), Kaoshiung City (KCI), Kaoshiung County (KCO) and Pingtung County (PCO), representing seven southern cities and counties. A total of 5452 urine samples was collected from July 2006 to December 2006 and subjected to screening for MA with enzyme immunoassay (EIA) and confirmed with GC-MS. As a result, MA positive percent and concentration were 10.9 ± 2.3% and 16535 ± 5682ng/mL, respectively. The positive percent for each location was TCI 14.4%, CCI 13.2%, PCO 11.3%, KCO 11.2%, CCO 9.0%, TCO 8.7% and KCI 8.7%. The mean concentrations of MA were: TCI 23892, TCO 20566, CCO 17877, KCO 17750, PCO 16260, KCI 13343 and CCI 6058 ng/mL.

並列關鍵字

methamphetamine drug abuse immunoassay GC-MS

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