RECURRENCE IMPACT OF PRIMARY SITE AND PATHOLOGIC STAGE IN PATIENTS DIAGNOSED WITH COLORECTAL CANCER

Wen-Chien Ting ； Yen-Chiao Angel Lu ； Chi-Jie Lu ； Chalong Cheewakriangkrai ； Chi-Chang Chang

《品質學報》 25卷3期 (2018/06) Pp. 166-184

https://doi.org/10.6220/joq.201806_25(3).0003

摘要

Detection of cancer recurrence for events of asymptomatic is highly related to the survival. In this study, we considered the variable screening mechanisms and four data mining techniques. The pathological data were obtained from Cancer Center of Chung Shan Medical University Hospital. Results show that primary site and pathologic stage are important independent risk factors. Before variable screenings showed that the highest of average accuracy and area under the curve (AUC) were: C5.0. Screening results of the colon site, the accuracy of ＜ IIb stage was the highest with support vector machine (SVM) (0.91), and that of ≥ IIb stage was the highest with extreme learning machine (ELM) (0.86). In the rectum site, the accuracy of ＜ IIb stage was the best with ELM (0.96), and that of ≥ IIb stage was the highest with multivariate adaptive regression splines (MARS) (0.89) and ELM (0.89). The results of this study provide that for recurrence detection in colorectal cancer patients can be used by clinicians to recommend adjuvant treatment.

關鍵字

recurrent colorectal cancer ； data mining techniques ； pathologic stage

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