We investigate the determinants of the overseas physical expansions of large global banks from the perspective of eclectic theory, using bank-level data of the top 1,000 banks. Results show that most ownership-specific, internalization and location advantage factors positively affect large banks' expansion motives or location choice, such as a bank's size and operational performance, commercial trade relationship, and environments with more banking opportunities, higher accessibility to the market, lower information costs, and famous financial centers. We also find that large banks from countries with different national income, bank development, or regions have different thoughts and strategies on overseas expansion.