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18F-FDG PET and 99m Tc-MDP Findings in McCune-Albright Syndrome

氟-18-去氧葡萄糖正子斷層造影及鎝-99m-MDP骨骼閃爍造影在McCune-Albright癥候群之表現

摘要


一位57歲女性至本院接受氟-18去氧葡萄糖正子斷層造影健康檢查,正子斷層造影結果顯示在左肩胛骨、左側肋骨及兩側股骨多處有氟-18-去氧葡萄糖吸收增加的現象。病人自述有纖维性發育不良、性早熟及甲狀腺功能亢進病史,也曾經因為甲狀腺功能亢進而接受過甲狀腺部分切除術及碘-131治療。為了瞭解多骨性纖維發育不良症病灶的範圍,病人於隔日接受鎝-99m-MDP骨骼閃爍造影檢查。結果顯示氟-18-去氧葡萄糖吸收增加的病灶位置和骨骼閃爍造影血池像相近,而延遲像开骼閃爍造影則另外在顱骨多處、左側肱骨及右側肋骨多處有吸收增加病灶。氟-18-去氧葡萄糖在纖維性發育不良症病灶處的吸收顯示和病灶處的血液灌流状態高度相關。

並列摘要


A 57-year-old female underwent whole-body 18F-fluorodeoxyglucosepositron emission tomography(FDG-PET)study for health examination. There is increased FDG uptake in the left scapula, the left side ribs and bilateral femora. Fibrous dysplasia, sexual precocity and hyperthroidism history was then told. She also received thyroidectomy and 131I radioiodine therapy for hyperthyroidism. She then underwent 99mTc-MDP bone scintigraphy the next day to evaluate the extent of polyostotic fibrous dysplasia. The location of FDG uptake showed similar pattern as the blood pool phase bone scintigraphy. Discrepancy was noticed in the skull, the left humerus and the right side ribs between FDGPET images and delayed phase bone scintigraphy. The image findings of this patient suggest that FDG uptake within the lesions of fibrous dysplasia is highly related to the blood perfusion status of the lesions.

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