- 期刊
葛瑞夫茲氏病氟-18-去氧葡萄糖正子斷層掃描：一病例報告
Elevated (superscript 18)F-FDG Uptake in Diagnosis of Graves' Disease: A Case Report
摘要
A 48-year-old woman complained of dizziness and general soreness for about 6 months. She underwent a whole- body (superscript 18)F-FDG PET study for physical check up. There were symmetric, diffuse high (superscript 18)F-FDG uptake in the thyroid and the thymus glands, psoas muscles and limb skeletal muscles. Further examinations showed increased thyroid function: T4 15.03μg/dl, T3 264.57ng/dl, TSH＜0.1μU/ml, antimicrosomal antibody 6400x, anticholinergic receptor antibody negative. The thyroid echo showed a diffusely enlarged and hypoechoic thyroid gland, which was compatible with Graves’ disease. The (superscript 99m)Tc thyroid scan had diffusely increased uptake of radioactivity, and the chest CT showed thymus hyperplasia. The radiolabeled (superscript 18)F-FDG PET were used to measure glucose metabolism in vivo. In patients with Graves’ disease, glucose metabolism was increased in the thyroid gland, and the blood flow of the skeletal muscles was also increased. Thymic hyperplasia is apparently associated with Graves’ disease. In this patient, the findings of increased uptake of (superscript 18)F-FDG PET in thyroid gland, thymus gland and skeletal muscles was compatible with glucose hypermetabolism in Graves’ disease. The experience of (superscript 18)F-FDG PET in patients with Graves’ disease is still limited, more studies is needed for further understanding of this disease.
並列摘要
A 48-year-old woman complained of dizziness and general soreness for about 6 months. She underwent a whole- body (superscript 18)F-FDG PET study for physical check up. There were symmetric, diffuse high (superscript 18)F-FDG uptake in the thyroid and the thymus glands, psoas muscles and limb skeletal muscles. Further examinations showed increased thyroid function: T4 15.03μg/dl, T3 264.57ng/dl, TSH＜0.1μU/ml, antimicrosomal antibody 6400x, anticholinergic receptor antibody negative. The thyroid echo showed a diffusely enlarged and hypoechoic thyroid gland, which was compatible with Graves’ disease. The (superscript 99m)Tc thyroid scan had diffusely increased uptake of radioactivity, and the chest CT showed thymus hyperplasia. The radiolabeled (superscript 18)F-FDG PET were used to measure glucose metabolism in vivo. In patients with Graves’ disease, glucose metabolism was increased in the thyroid gland, and the blood flow of the skeletal muscles was also increased. Thymic hyperplasia is apparently associated with Graves’ disease. In this patient, the findings of increased uptake of (superscript 18)F-FDG PET in thyroid gland, thymus gland and skeletal muscles was compatible with glucose hypermetabolism in Graves’ disease. The experience of (superscript 18)F-FDG PET in patients with Graves’ disease is still limited, more studies is needed for further understanding of this disease.
延伸閱讀
- Tsai, Y. C., Dai, Y. C., & Wu, W. F. (2017). 氟-18去氧葡萄糖正子掃描偵測口腔梭狀細胞癌的心臟轉移. 核子醫學暨分子影像雜誌, 30(3), 137-141. https://doi.org/10.6332/ANMMI.3003.007
- Chen, Y. L., Lin, K. J., Chou, H. H., & Yen, T. C. (2007). 復發性子宮頸癌罕見之廣泛性皮下組織轉移之氟－18-去氧葡萄糖正子掃描影像的病例報告. 核子醫學雜誌, 20(2), 93-99. https://doi.org/10.6332/ANMS.2002.005
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- Ding, P. C., Tsai, R. K., & Sun, C. Y. (1999). Fibrous Dysplasia Associated with Optic Atrophy-A Case Report. 中華民國眼科醫學會雜誌, 38(2), 268-272. https://doi.org/10.30048/ACTASOS.199906.0010
- 喬桓、陳良城、黃國書、蔡高宗（2002）。Diffuse Idiopathic Skeletal Hyperostosis: A Case Report。中華民國復健醫學會雜誌，30(3)，171-181。https://www.airitilibrary.com/Article/Detail?DocID=10253009-200209-30-3-171-181-a