Technetium-99m ECD Brain Single Photon Emission Computed Tomography in a Patient with Delayed Neurological Sequelae after Carbon Monoxide Poisoning

鎝-99m-ECD腦SPECT評估一氧化碳中毒後延遲神經病變：一病例報告

黃淑華(Shu-Hua Huang) ； 張瓊之(Chang Chiung Chih) ； 黃玉兒(Yu-Erh Huang) ； 王佩文(Pei-Wen Wang) ； 李將瑄(Chiang-Hsuan Lee)

《核子醫學雜誌》 18卷1期 (2005/03) Pp. 57-61

https://doi.org/10.6332/ANMS.1801.008

摘要

一位45歲男性病患一氧化碳中毒一個月後出現延遲神經病變，接受鎔-99m-ECD腦SPECT檢查。第一次腦SPECT在出現延遲神經病變後顯示整個大腦皮質重度低血流。三個月後追蹤腦SPECT顯示大腦皮質血流量有增加但兩側額葉未完全回復，與臨床病情發展相一致。這些變化與腦部斷層及核磁共振掃描作一對比。相較臨床及腦部斷層或核磁共振掃描，SPECT腦部造影是否可用以診斷或評估一氧化碳中毒之預後將加以討論。

關鍵字

鎝-99m-ECD ； 腦SPECT ； 一氧化碳中毒

並列摘要

Single photon emission computed tomography (SPECT) with technetium-99m ethyl cysteinate dimmer ((superscript 99m)Tc-ECD) performed in a 45-year-old male patient with delayed neurological sequelae after carbon monoxide (CC) poisoning about one month after anoxic insult. The initial brain SPECT at delayed onset of neuropsychiatric symptoms showed high-grade hypoperfusion images throughout the cerebral cortex. The follow- up SPECT examination performed 3 months after initial scan showed the diffuse hypoperfusion images had become lighter but remained to a degree in bilateral frontal lobes, paralleled by clinical outcome. Any change in cerebral blood flow was correlated with clinical or brain CT or MRI evidence of delayed deficits in this case. The high utility of SPECT brain imaging in determining the diagnosis or prognosis of CO poisoning was discussed in comparison with brain CT or MRI findings.

並列關鍵字

(superscript 99m)Tc-ECD ； brain SPECT ； CO poisoning