- 期刊
Comparison of Double Phase (superscript 99m)Tc-MIBI Parathyroid Scan with Ultrasonography in Secondary Hyperparathyroidism: A Preliminary Study
雙時像鎝－99m-MIBI副甲狀腺攝影和超音波在續發性副甲狀腺亢奮的比較：初報
摘要
背景：本研究之目的主要針對臨床上運用雙時像鎝－99m-MIBI副甲狀腺攝影和超音波診查續發性副甲狀腺充奮的比較。 方法：從2002年5月到2004年9月總共有11位血液透析被診斷為續發性副甲狀腺亢奮的病人，他們做過全副甲狀腺切除術，每個人手術前兩週也接受雙時像鎝－99m-MIBI副甲狀腺攝影和頸部超音波。此外，每個人都有完整的病理報告和抽血檢查。 結果：雙時像鎝－99m-MIBI副甲狀腺攝影的敏感度是以病人為依據的90.9%(10/11)，以及以病灶為依據的56.1%(23/41)。同時頸部超音波的敏感度也分別是90.9%(10/11)和56.1%(23/41)。這兩種儀器並沒有統計學上的差異。合併使用雙時像鎝－99m-MIBI副甲狀腺攝影和頸部超音波可以改善以病灶為依據的敏感度到78.05%(32/43)。 結論：雙時像鎝－99m-MIBI副甲狀腺攝影對於續發性副甲狀腺亢奮的偵測是一個不錯的選擇，搭配頸部超音波可以檢測出更多的病灶。
並列摘要
Background: The aim of this study was to evaluate the clinical application of double phase (superscript 99m)Tc-MIBI parathyroid scan and compare it with ultrasonography in secondary hyperparathyroidism. Methods: From May, 2002 to September, 2004, 11 patients with uremia under hemodialysis and diagnosis of secondary hyperparathyroidism were enrolled. Double phase (superscript 99m)Tc-MIBI parathyroid scintigraphy and ultrasonography of neck were done 2 weeks before total parathyroidectomy. All patients had pathologic report after surgery. Results: The patient-based and lesion-based sensitivity of double phase (superscript 99m)Tc-MIBI parathyroid scan were 90.9% (10/11) and 56.1% (23/41). Meanwhile, those of ultrasonography were 90.9% (10/11) and 56.1% (23/41), respectively. These two modalities show no statistical difference. The combination of ultrasonography and scintigraphy resulted in improved lesion-based sensitivity to 78.05%. Conclusions: Double phase (superscript 99m)Tc-MIBI parathyroid scan is a good choice for survey of secondary hyperparathyroidism. Assistant with ultrasonography could detect more lesions in secondary hyperparathyroidism.
延伸閱讀
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