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Negative Impact of 18F-FDG PET for Restaging in a Case of Recurrent Buccal Cancer

氟-18去氧葡萄糖正子斷層攝影應用於一口腔癌復發病例的再分期之負面效應

摘要


氟-18去氧葡萄糖正子斷層攝影被證實應用在頭頸部癌症復發再分期上是有價值的。我們報告一位口腔癌復發病例,正子斷層攝影檢查認為有縱膈腔淋巴結之遠端轉移,而後經縱膈腔鏡切片證實為肺結核感染,是一偽陽性結果。救援手術施行後,頸部淋巴結發現有囊外擴散,病患因此接受同步化學放射療法,目前無疾病跡象達四個月。我們建議,在放棄救援治療前,正子斷層攝影的結果是必定需要經由組織病理學的證實。

並列摘要


Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) has proved to be a valuable tool in the restaging of recurrent head and neck cancer. Herein, we report a case of recurrent buccal cancer with false-positive findings of mediastinal lymph node metastases in a FDG PET study. The FDG PET positive lesion was finally proved to be tuberculosis by the mediastinoscope. After salvage surgery, extracapsular spread of neck lymph node was detected. The patient subsequently received concurrent chemoradiotherapy and was disease-free up to 4 months after his salvage therapy. We suggested that a histopathological confirmation of PET findings is mandatory in certain cases before abandoning salvage treatment.

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