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蒙地卡羅模擬應用於個人化腫瘤假體模型之劑量評估

Dose Evaluation of Personal Tumor Models Using Monte Carlo Simulation

摘要


MIRDOSE爲一套核醫界常用的體內劑量計算程式,其根據S-值進行列表,具有快速計算的優點。然而,MIRDOSE程式對於腫瘤劑量的計算是以固定質量的圓球來模擬腫瘤,並未考慮腫瘤的幾何特性,因此降低了劑量評估的準確性。本研究利用蒙地卡羅模擬技術來開發一套個人化腫瘤模型之劑量評估系統,以更準確的評估體內劑量,並分析不同幾何特性之腫瘤模型其自吸收之差異。

並列摘要


MIRDOSE is the most popular software for calculating internal organ doses in the nuclear medicine community. It uses the tabulated S-values. Therefore, MIRDOSE has the main advantage of improving the computational speed. However, the use of fixed-mass spheres as tumor models cannot take the geometric characteristics of the real tumor into account, compromising the accuracy of dose evaluation. In this study, different masses and shapes of tumor models were simulated using the Monte Carlo N-Particle (MCNP) code to accurately estimate the tumor doses. Percent dose errors were analyzed as well.

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