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Normal Pressure Hydrocephalus: Scintigraphic Findings on SPECT/CT Image

正常腦壓水腦症:融合電腦斷層模組之單光子斷層造影的表現

摘要


一位65歲女性於2007年3月遭受頭部創傷,產生蜘蛛膜下腔出血及水腦症,於是病患接受腦室腔分流(VP shunt)手術。然而,病患卻漸漸虛弱,並且疾病進程演變成緘默症。為了瞭解腦脊髓液的動態,我們替病患進行腰椎穿刺,於腦脊髓膜內注射了6 mCi的鎝-99m-DTPA,並施行腦池造影。平面影像顯示典型的正常腦壓水腦症之心形顯影,我們同時收取融合電腦斷層模組之單光子斷層造影(SPECT/CT),其橫切面影像顯現左右兩側側腦室活性攝取的蝴蝶形狀標誌。相較於平面影像,SPECT/CT影像更容易清楚地讓核醫醫師一眼就能判別出側腦室放射活性積聚的情形,對正常腦壓水腦症的診斷變得更容易、更精確。

並列摘要


A 65-year-old woman sustained a head injury, subarachnoid hemorrhage (SAH), and hydrocephalus. A ventriculoperitoneal shunt was subsequently implanted. However, the patient developed general weakness and mutism. Clinical evaluation revealed that the shunt was patent. Cisternography was performed by direct intrathecal administration of 6 mCi of technetium-99m diethylene triamine pentaacetic acid (99mTc-DTPA) by means of a lumbar puncture. The planar images showed the classic heart-shaped pattern of normal pressure hydrocephalus (NPH). Cisternography using SPECT/CT was also performed and revealed that the butterfly shape of increased radioactivity was clearly and definitely located in the bilateral lateral ventricles with the help of CT images. Compared with traditional planar images, the SPECT/CT makes the diagnosis of NPH more accurate and easier.

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