Significant ground settlement has been observed from time to time during shield tunneling when backfill grout injection is not carried out accurately. It becomes more popular to use secondary grout injection at the proper time before the influence of ground loss to the surrounding medium extended to ground surface and to prevent/or reduce the ground settlementThis paper will begin with explaining the relation between ground loss, backfill grout injection, and ground settlement. It also discribes the mechanism and application of secondary grout injection in reducing ground settlement. Case study focusing on the timing, area, construction management, material and effects of the secondary grout injection will also be given. It is expected that this paper can provide some valuable data for similar case in the future.