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修正簡易營養評估量表(MNA)以改善其評估血液透析患者營養風險之效能

Modifying the Short-form Mini-Nutritional Assessment to Improve the Prediction of Nutritional Risk in Patients on Hemodialysis

摘要


目標:改良MNA(Mini-Nutritional Assessment)使其更適用於血液透析(hemodialysis, HD)患者的營養評估。方法:本研究徵求中部某地區醫院門診洗腎中心血液透析患者100名(18-97歲,男43女57名)。經同意後,以短式及長式MNA-台灣二版評估營養狀況並與生化指標比較。MNA台灣二版為採用台灣老人體位指標的改良版。版本之修正以選擇較能反應HD病情的非短式題項(如O題)與較不反應HD病情的短式題項(如E題)互換題位,並檢定其改良成效。以Wilcoxon Signed-Rank Test進行事後檢定,比較短式MNA台灣二版各改良版本與長式MNA台灣二版的評估結果。以Pearson's相關分析長式及各短式MNA台灣二版的總分與血清白蛋白、血清肌酸酐、住院天數、及急診次數的相關性。結果:本研究發現短式MNA台灣二版用於評估血液透析病患時,以量表O題(自評營養狀況)取代(對換)E題(失智),最能改進評估功能,且其評估成果與長式MNA台灣二版相當一致。結論:本研究的結果顯示MNA量表以O題(自評營養狀況)取代(對換)E題(失智)或D題(精神壓力)最能改進其血液透析患者的評估功能。此簡單的改良,使短式MNA量表可適用於台灣的血液透析患者。

並列摘要


Objectives: To modify the Mini-Nutritional Assessment (MNA) so that it would be suitable for use in hemodialysis (HD) patients. Methods: Subjects were 100 HD outpatients (18-97 years of age, 43 men and 57 women) recruited from a district hospital in Central Taiwan. With their consent, we rated the nutritional status of each subject with the long-, short-, and modified short-form versions of the MNA and measured their biochemical values. We examined various alternative short-form versions of the MNA based on the dietary characteristics of HD patients. The study used the Wilcoxon Signed-Rank Test, Pearson's correlation analysis and the crosstabulation test to evaluate the ability of the short-form versions to predict the long-form MNA (T2). Results: Results showed that a modified short-form version that exchanged item O (selfrated nutritional status) for item E (dementia) improved the predictive ability of the MNA in HD patients. The modified short-form performed well compared to the long-form. Conclusions: The study demonstrated that replacing item O for E or D in the MNA can best improve the functionality of the MNA. This simple revision makes the short-form suitable for assessing the risk of malnutrition in patients on hemodialysis.

參考文獻


Cooper, B. A.,Penne, E. L.,Bartlett, L. H.,Pollock, C. A.(2004).Protein malnutrition and hypoalbuminemia as predictors of vascular events and mortality in ESRD.Am J Kidney Dis.43,61-6.
How, P. P.,Lau, A. H.(2004).Malnutrition in patients undergoing hemodialysis: is intradialytic parenteral nutrition the answer?.Pharmacotherapy.24,1748-58.
Foley, R. N.,Parfirey, P. S.,Harnett, J. D.,Kent, G. M.,Murray, D. C.,Barre, P.(1996).Hypoalbuminemia, cardiac morbidity, and mortality in end-stage renal disease.J Am Soc Nephrol.7,728-36.
Feroze, U.,Noori, N.,Kovesdy, C. P.(2011).Quality-of-life and mortality in hemodialysis patients: roles of race and nutritional status.Clin J Am Soc Nephrol.6,1100-11.
de Castro, M. C.,de Oliveira, F. C.,da Silveira, A. C.(2010).Importance of the monthly biochemical evuluation to identify patients on hemodialysis with malnutrition.J Bras Nefrol.32,349-54.

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