We investigated whether a gender bias exists in considering reperfusion therapy for patients with acute myocardial infarction. We retrospectively reviewed 209 patients (152 men and 57 women) with acute myocardial infarction from January 1998 to February 2000. The women were significantly older than the men (71.1±15.5 years vs. 60.6±12.8,P<0.001), and had higher incidences of diabetes (33/57 vs. 43/152, P = 0.001) and hypertension (49/57 vs. 70/152, P = 0.018) but a lower incidence of smoking (10/57 vs. 107/152,P<0.00001).The “onset-to-door” time and the “door-to-reperfusion” time were similar between the two genders. No differences could be found in location and extent of coronary artery disease. However, there was a significant difference in the use of reperfusion therapy between the men and the women (129/152 vs.26/57,P<0.0001).Multivariate regression analysis model indicates that gender instead of age was the only independent factor. In conclusion, our study revealed that there are gender differences between men and women in referral to reperfusion therapy for acute myocardial infarction in Taiwan.
We investigated whether a gender bias exists in considering reperfusion therapy for patients with acute myocardial infarction. We retrospectively reviewed 209 patients (152 men and 57 women) with acute myocardial infarction from January 1998 to February 2000. The women were significantly older than the men (71.1±15.5 years vs. 60.6±12.8,P<0.001), and had higher incidences of diabetes (33/57 vs. 43/152, P = 0.001) and hypertension (49/57 vs. 70/152, P = 0.018) but a lower incidence of smoking (10/57 vs. 107/152,P<0.00001).The “onset-to-door” time and the “door-to-reperfusion” time were similar between the two genders. No differences could be found in location and extent of coronary artery disease. However, there was a significant difference in the use of reperfusion therapy between the men and the women (129/152 vs.26/57,P<0.0001).Multivariate regression analysis model indicates that gender instead of age was the only independent factor. In conclusion, our study revealed that there are gender differences between men and women in referral to reperfusion therapy for acute myocardial infarction in Taiwan.