Past studies have indicated that long-term exposure to vibration environment of staff, could easily lead to whole body vibration (WBV) hazards.The resonance of spine and organ system related to vibration causes harm to vertebral bones and peripheral nerve system. It induces spinal degeneration, disc herniation, sciatica, lower back pain and other diseases. To determine whether whole-body vibration has caused the disc herniation bases on: 1. Evidence of the disease; 2. evidence of occupational exposure; 3. the time interval between first asbestos exposure and begining of disease; 4. reasonably excluding other risk factors; 5. evidence of epidemiology. This article is a case reported about a bus driver, suffering from herniation of lumbar intervertebral disc related to whole-body vertical vibration. It is expected that, on the basis of the related literature, this article could provide more information for the clinicians.