Three kind of non-toxic agricultural wastes including rice hull, rice straw and corn cob could be used as a good medium, if the nutrients were added in mushroom culture.The wooden ear, oyster mushroom and shiitake could also be normally cultured on the cultured on the corn cob medium.The use of corn cob as the cultural medium can solve the shortage problem of lumber or saw dust, which used to be taken as the cultural medium for mushroom.