The characteristics of Titanium wire have high Specific strength, nonmagnetic, and excellent corrosion-resisting properties, which make it beneficial for development. Except for defence and aviation, the demand for Titanium wire in the commodity increase substantially in recent years and there is enormous market in medical instruments because of the excellent biocompatibility. Due to it is difficult for metal forming, the cost of the process is too expensive, and influences the promotion of Titanium wire. It is necessary for the process research according to the wire-drawing theory, establishing the Titanium lubrication technology, and the tests of the friction factor, and they can reduce the difficult of procedure and advance the quality. There are many new wire-drawing technologies in this paper, and they can be the methods to solve to process the hard-forming material in the future.