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Endobronchial Actinomycosis with Nontuberculous Mycobacterial Colonization: A Case Report and Literature Review

支氣管放線菌症合併肺部非結核性分枝桿菌症:病例報告及文獻回顧

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摘要


放線菌症是由以色列放線菌所引起的慢性肉芽腫疾病,它具有化膿、膿瘍形成或甚至形成多個引流瘻管。有多種疾病疑似肺部放線菌症。我們報告一位以慢性咳嗽併多量痰液的六十歲女性。痰液抗酸性塗片為陽性且培養結果為非結核分枝桿菌。光纖支氣管鏡檢查顯示支氣管性腫瘤併支氣管狹窄。切片生檢組織學檢查證實為放線菌感染且對青黴素靜脈給藥有效。

並列摘要


Actinomycosis is a chronic granulomatous disease caused by the fungus Actinomyces israelii, and is characterized by suppuration, abscess formation, and eventually the development of multiple drainage sinuses. The number of lesions that mimic actinomycosis of the lung is extensive. We report a case of a 60-year-old women who presented with chronic cough and profuse sputum. The sputum acid-fast stain showed positive (one plus) and the culture yielded nontuberculous mycobacterium. Fiberoptic bronchoscopy revealed an endobronchial tumor with stenotic bronchus. Histologic examination of the biopsy specimen demonstrated Actinomyces infection. There was a clinical response to penicillin therapy.

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