Well-differentiated Fetal Adenocarcinoma of the Lung: Report of a Case in a 27-year-old Female

分化良好的肺部胎兒型腺癌：一位27歲女性的病例報告

林佳衡(Chia-Heng Lin) ； 高尚志(Shang-Jyh Kao)

《胸腔醫學》 19卷1期 (2004/02) Pp. 55-59

摘要

肺母細胞瘤是一種罕見的，在顯微鏡下酷似胎兒肺部的惡性腫瘤。最近有人將它再細分為三類，就是︰典型雙相的肺母細胞瘤，分化良好的胎兒型腺癌，與肋膜肺母細胞瘤。分化良好的胎兒型腺癌在西元1982年由Kradin等人首度提出，包含肺母細胞瘤的表皮特徵，卻缺乏肺母細胞瘤的肉瘤特微。在此我們報告一位27歲的女性病患，表現為一右肺中葉的腫瘤，病理切片下為許多分支的管狀結構，形成篩狀的腫瘤，由偽多層，無纖毛的柱狀細胞與腺狀表皮下的細胞團“桑葚胚”所構成。其組織學特徵符合分化良好的胎兒型腺癌之定義。在接受右肺中葉切除術後，患者在三個月的追蹤期間內狀況良好。

關鍵字

分化良好的胎兒型腺癌

並列摘要

Pulmonary blastomas are a group of rare malignant neoplasms that microscopically resemble the fetal lung and have recently been subdivided into three categories: classic biphasic pulmonary blastoma (CBPB), well-differentiated fetal adenocarcinoma (WDFA), and pleuropulmonary blastoma (PPB). WDFA was first described by Kradin et al in 1982 as a tumor containing the epithelial features of pulmonary blastoma, but lacking sarcomatous features. Herein we report a 27-year-old female patient with a right middle lobe tumor, which consisted of branching tubules of a cribriform pattern lined by pseudostratified, nonciliated columnar cells and some morules beneath the glandular epithelium. The histological features fulfilled the criteria of a well-differentiated fetal adenocarcinoma. She underwent a right middle lobe lobectomy, and was well at the 3-month follow-up.

並列關鍵字

well-differentiated fetal adenocarcinoma