Secondary Sjögren's Syndrome Complicated with Multiple Pulmonary Cysts and Lymphocytic Interstitial Pneumonitis-A Case Report and Literature Review

次發性修格蘭症候群併發多發性肺囊腫及淋巴性間質性肺炎－一病例報告及文獻回顧

蘇文麟(Wen-Lin Su) ； 陳健文(Chien-Wen Chen) ； 蔡鎮良(Chen-Liang Tsai) ； 吳孟珍(Meng-Chen Wu) ； 蘇麗慧(Li-Hui Soh) ； 吳清平(Chin-Pyng Wu)

《胸腔醫學》 19卷6期 (2004/12) Pp. 509-516

https://doi.org/10.29806/TM.200412.0012

摘要

前言：修格蘭症候群(sjögren's syndrome)的特徵為外分泌線體淋巴球浸潤，可能合併有呼吸道疾病的表現。在此提出一病例為次發性修格蘭症候群併發多發性肺囊腫(multiple pulmonary cysts)。
病例報告：一位四十九歲女性因胸部X光片發現多謄性肺囊腫而住院，住院前一星期有咳淡綠色痰液情形，在住院前三天始有發燒及發冷症狀。經過系列檢查確定診斷為類風濕性關節炎併次發性修格蘭症候群；胸腔電腦斷層檢查證實有多發性肺囊腫且符合淋巴性間質性肺炎(lymphocytic interstitial pneumonitis) 影像。
討論：多發性肺囊腫有很多可能的原因，吐氣高解析胸腔電腦斷層是診斷多發性肺囊腫及淋巴性間質性肺炎最有幫助的檢查工具；以類固醇治療林巴性間質性肺炎有很好的效果，因此早期診斷將對病患有所助益。

關鍵字

修格蘭症候群 ； 肺囊腫 ； 淋巴性間質性肺炎 ； 類風濕性關節炎

並列摘要

Sjögren's syndrome is characterized by lymphocytic infiltration of the exocrine glands, possibly with respiratory findings. We present a 49-year-old woman with secondary Sjögren's syndrome and pulmonary cysts. One week before her admission, she had a cough with copious, light- green sputum. Chills and fever developed over a period of 3 days. Rheumatoid arthritis and secondary Sjögren's syndrome were eventually diagnosed. The chest computed tomography and pathologic reports showed pulmonary cysts with lymphocytic interstitial pneumonia. Expiratory high-resolution CT is the best method for evaluating pulmonary cysts with this pneumonia. Outcomes in lymphocytic interstitial pneumonia are good with early diagnosis and corticosteroid treatment.

並列關鍵字

pulmonary cyst ； rheumatoid arthritis ； Sjögren's syndrome ； lymphocytic interstitial pneumonitis