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Esophageal Stricture Induced by Chemo-radiotherapy-A Case Report

合併化學治療及放射治療引起的食道狹窄-病例報告

摘要


在過去因高劑量放射治療引起的食道病變並非罕見的併發症,且有急性和慢性之分。發生機會似乎隨合併化學治療及放射治療而增加。我們提出一位肺癌病患,於接受合併化學治療及放射治療後,發生食道狹窄的併發症,並討論該患者使用之化學治療藥物是否影響食道狹窄之發生。另整理現行之內外科治療方式。

並列摘要


Esophageal complications induced by radiotherapy are not uncommon. Although esophageal stricture after radiotherapy still is a relatively rare complication, the incidence and severity of esophagitis has increased when radiotherapy is combined with chemotherapy. We present a patient with stage Ⅲb adenocarcinoma of the lung, who developed esophageal stricture after induction chemotherapy, followed by concurrent chemo-radiotherapy. The chemotherapeutic agents that might increase the effects of radiation are reviewed. For the management of patients who developed esophageal stricture, medical treatment with supportive care is usually used. Balloon dilatation is another choice. However, the recurrence rate is high. Surgical intervention is used when medical treatment is ineffective.

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