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Esophageal Gastrointestinal Stromal Tumor Presenting as a Mediastinal Mass-A Case Report

以縱膈腔腫塊為表現的食道腸胃道實質腫瘤-病歷報告

摘要


食道腸胃道實質腫瘤是一種腸胃道非上皮性實質腫瘤。近可從食道下端,遠可至肛門的腸胃道發生此種腫瘤。然而,食道腸胃道實質腫瘤以縱膈腔腫塊為表現的病例卻很少被報告。在此,我們提出一個發生在51歲男性,以間歇性腹痛為最初表現,生理檢查發現有腹部腫瘤,放射線檢查卻發現,病因為縱膈腔腫塊的少見的病例。 除此之外,我們還討論重要的鑑別診斷,及放射線檢查可能提供的線索,用以做為手術前評估。因為,如同已報導的研究指出,tyrosine kinase抑制劑可以縮小腸胃道實質腫瘤。如此,內服藥物有機會提高腫瘤的可手術性及器官保留的範圍,使得對於這種以縱膈腔腫塊為表現的食道腸胃道實質腫瘤的術前評估,更顯重要。

並列摘要


Gastrointestinal stromal tumors (GIST) are primary non-epithelial mesenchymal neoplasms of the gastrointestinal tract. They can arise anywhere from the lower esophagus to the anus. However, an esophageal GIST presenting as a mediastinal mass has rarely been reported. We present such a patient and discuss the importance of the differential diagnosis of a mediastinal mass. Since GIST may respond to a tyrosine kinase inhibitor, diagnosing this tumor before extensive surgery is crucial.

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