- 期刊
Pulmonary Infection with Mycobacterium Simiae-A Case Report
肺部的Mycobacterium simiae感染－病例報告
摘要
Mycobacterium simiae在人類的感染自1971年開始被發現。M. simiae造成的感染似乎有地域性的分佈，大多數多是在熱帶及亞熱帶地區發現。肺部M. simiae感染的病例在慢性肺部、肺結核病、惡性腫瘤及後天免疫不全症候群的病人中都有被描述過，瀰漫性的M. simiae感染也曾被報告過。因為病人數太少，針對肺部M. simiae感染最理想的治療方式仍然不是很清楚。這篇文章報告了台灣第一個慢性阻塞性肺病病人肺部感染M. simiae的病例，而且成功的以clarithromycin及rifampicin治療。我們並對有關M. simiae 的流行病學、傳播途徑、臨床症狀、細菌學的特性、診斷的標準及目前建議的治療方式做一些整理。
並列摘要
Mycobacterium simiae infections in humans have been reported since 1971, and are found mostly in tropical and subtropical regions. Pulmonary M. simiae infections have been presented in patients with chronic lung disease, pulmonary tuberculosis, malignancy, and acquired immunodeficiency syndrome. The optimal therapy for pulmonary M. simiae infection is not clear due to limited patient numbers. This report describes the first case of pulmonary M. simiae infection in Taiwan, found in a patient with chronic obstructive pulmonary disease who was successfully treated with clarithromycin and rifampicin. The prevalence, reservoir, clinical presentation, bacterial characteristics, diagnostic criteria, and current recommended therapy for M. simiae infection are also reviewed.
延伸閱讀
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