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Malignant Giant Solitary Fibrous Tumor of the Anterior Mediastinum-A Case Report

巨大單獨之前縱膈腔惡性纖維瘤-病例報告

摘要


一位六十七歲女性表現呼吸漸進性急促大於六個月。胸腔放射線檢查與電腦斷層顯示有一巨大肺外硬腫瘤在左側胸腔中且合併有一些肋膜積水。這腫瘤壓迫了縱膈腔與左肺。施以左外側開胸輔以內視鏡手術將腫瘤清楚且完整地移除。在手術中發現一個巨大紅色硬的腫瘤體積有225x170x90公分而重量有2.6公斤。病理診斷為單獨的惡性纖維瘤。組織檢查顯示這單獨的纖維瘤由少至多相對均勻且溫和分佈在纖維與黏液基質中的梭狀細胞所主組成。術後經過二年的追蹤這病人仍然保持良好。

並列摘要


A 67-year-old female presented with progressive shortness of breath for more than 6 months. Chest radiographs and a computed tomography scan showed a giant extra-pulmonary solid mass in the left thoracic cavity with minimal pleural effusion. The mass compressed the mediastinum and left lung. A left lateral video-assisted thoracotomy was performed and the clearly demarcated mass was removed. A giant reddish solid mass measuring 22.5×17.0×9.0 cm and weighing 2.6 kg was found during operation. The pathological diagnosis was malignant solitary fibrous tumor. Histological examination showed a solitary fibrous tumor composed of a relatively uniform, bland hypocellular to hypercellular spindle cell population in collagenous, cellular and myxoid stroma. The patient remained well during a 2-year follow-up after the operation.

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