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Acute Renal Failure and Hypercalcemia: Rare Initial Manifestations of Sarcoidosis-A Case Report

急性腎衰竭及高血鈣:以罕見的初始症狀表現之類肉瘤病-病例報告

摘要


類肉瘤病乃一全身性發炎的疾病,可以侵犯任何器官,尤其是肺部。雖然所有器官都可能受侵犯,但侵犯到腎臟卻是相當罕見。 我們報告了一個58歲男性病人,因為持續惡心、嘔吐三個月而住院。實驗室檢查發現血液肌酸酐及血鈣升高。最後,我們經由胸部x光片,核醫嫁67發炎掃瞄(Gallium-67citrate scanning),縱膈腔淋巴結切片檢查,及腎臟切片檢查確定診斷病人罹患類肉瘤病併腎臟及內分泌系統侵犯。病人在接受類固醇治療後,腎功能及血鈣皆逐漸獲得改善。

並列摘要


Sarcoidosis is a multisystem, inflammatory disorder that can involve any organ, especially the lungs; however, significant renal involvement is rare [1]. We report a 58-year-old male who had nausea and vomiting for 3 months. Laboratory data showed elevated serum creatinine and calcium levels. Sarcoidosis with renal and endocrine gland involvement was confirmed by typical chest radiography findings, Gallium-67 citrate scanning, mediastinoscopic biopsy of the mediastinal lymphadenopathy, and kidney biopsy. Oral prednisolone, 0.5 mg/kg/day, resulted in laboratory improvement.

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