Sarcoidosis is a multisystem, inflammatory disorder that can involve any organ, especially the lungs; however, significant renal involvement is rare [1]. We report a 58-year-old male who had nausea and vomiting for 3 months. Laboratory data showed elevated serum creatinine and calcium levels. Sarcoidosis with renal and endocrine gland involvement was confirmed by typical chest radiography findings, Gallium-67 citrate scanning, mediastinoscopic biopsy of the mediastinal lymphadenopathy, and kidney biopsy. Oral prednisolone, 0.5 mg/kg/day, resulted in laboratory improvement.