Diffuse Endobronchial Kaposi's Sarcoma in a Patient with Human Immunodeficiency Virus Infection-A Case Report and Literature Review

人類免疫不全病毒感染患者之瀰漫型氣管內卡波西氏肉瘤

張志誠(Chih-Cheng Chang) ； 王智亮(Chih-Liang Wang) ； 李岡遠(Kan-Yuan Li) ； 薛純(Chuen Hsueh) ； 林鴻銓(Horng-Chyuan Lin)

《胸腔醫學》 22卷5期 (2007/10) Pp. 344-350

https://doi.org/10.29806/TM.200710.0007

摘要

卡波西氏肉瘤，是一種在後天免疫不全患者身上常見的症候。其表現常為表皮腫瘤或林巴結腫大為主要症狀。但在本例中卻以肺部症狀為主要表現。
我們報告一位由於以咳血與胸悶症狀求診，26歲年輕男性。一開始的表現是香燒及間歇性咳血痰。經一系列檢查之後，後天免疫不全及瀰漫性卡波西氏肉芽腫被診斷出來。我們的結論是，在有胸部X光有結節症狀及咳血的年輕病人，且若無吸煙病史者應懷疑是否有其他異於肺部感染外的病灶，除了較常見的肺癌外，應該要將氣管內卡波西氏肉瘤考慮其中。

關鍵字

氣管內卡波西氏肉瘤 ； 後天免疫不全症候群 ； 人類免疫不全病毒

並列摘要

Kaposi's sarcoma, a major complication in homosexual or bisexual acquired immunodeficiency syndrome (AIDS) patients, is a ubiquitous disease marked by cutaneous tumor and lymphadenopathy in the dermal and visceral organs. Cutaneous and gastrointestinal tract Kaposi's sarcoma is common, but respiratory system involvement is rare. This report describes a young male AIDS patient suffering from endobrochial Kaposi's sarcoma without cutaneous involvement. Multiple solid endobronchial tumors were characterized by a glinting surface under bronchoscopy. The endobronchial nodules regressed after 3 months of treatment with highly active antiretroviral therapy, including Combivir (Lamivudine 150 mg + Zidovudine 300 mg) twice a day, Lopinavir 800 mg per day and Ritonavir 200 mg per day. The possibility of endobronchial Kaposi's sarcoma should be considered in HIV patients suffering from chronic cough beyond opportunistic infection.

並列關鍵字

Endobronchial Kaposi's sarcoma ； acquired immunodeficiency syndrome