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Primary Lymphoepithelioma-like Carcinoma of the Lung: A Case Report

罕見的原發性肺部腫瘤:病例報告

摘要


一個51歲已婚男性,因身體健康檢查偶然發現右下肺葉腫瘤。病人不抽煙且除了輕微糖尿病,沒有過去重大病史。沒有呼吸道或全身性症狀。胸部X光及電腦斷層等檢查顯示右下肺葉腫瘤,除了疑似右肺門淋巴結腫大,未發現有遠處轉移現象。經手術切除,病理檢查結果為罕見的原發性類淋巴上皮癌(lymphoepithelioma-like carcinoma of the lung)。原位雜交法(in situ hybridization)證實Epstein-Barr virus的存在。 原發性類淋巴上皮癌是一種相當罕見的肺部腫瘤。世界衛生組織在1982年公佈的肺癌分類上,仍未將此腫瘤列入。在此我們報告這一例罕見的原發性肺癌並探討文獻關於此疾病之特色。

並列摘要


A 51-year-old man was found incidentally to have a mass at the lower lobe of the right lung incidentally. He was asymptomatic and was a non-smoker, and his health condition had been good. The chest radiograph showed a mass lesion at the lower lobe of the right lung and subsequent examination favored primary lung cancer. Surgical resection of the tumor was performed and the pathological examination revealed distinct features compatible with lymphoepithelioma-like carcinoma of the lung. In situ hybridization further confirmed the presence of EBER-1 (EBV-encoded small nuclear RNA-1). Primary lymphoepithelioma-like carcinoma of the lung is a rare pulmonary lung cancer. Prior to 1982, the WHO lung cancer classification did not include this rare entity. Herein we present a rare case of this type of cancer and review the literatures.

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