Pulmonary Primitive Neuroectodermal Tumor Associated with Digital Clubbing-A Case Report

杵狀指是肥厚性骨頭關節病變的其中一種表徵，並與許多種類的內科疾病包括感染、發炎、發紺性心臟病及腫瘤等有相關。傳統上認為杵狀指與肺癌有相關聯。在肺癌中杵狀指的發生率約10-29%，相較於小細胞癌更容易發生於非小細胞癌。我們在此報告一個罕見的肺部原始性神經外胚層腫瘤合併有杵狀指的個案。一個56歲男性在最近的五個月內發生了漸進的呼吸性氣促，伴隨有咳嗽，腹脹及體重減輕10公斤。經檢查發現兩手有明顯的杵狀指。影像學檢查顯示了左肺有巨大的腫瘤。經實行超音波導引切片術後病理報告為原始性神經外胚層腫瘤。病人接受了包含Doxorubicin, Decarbazine及Ifosfamide的化學治療。病人在治療後感覺氣促的症狀有漸漸改善

關鍵字

指甲；肺腫瘤；肥厚性骨頭關節病變

並列摘要

Digital clubbing, one of the syndromes of hypertrophic osteoarthropathy, is associated with many types of medical illness, including infectious, inflammatory disease, cyanotic heart disease and neoplasm. Classically, digital clubbing has been thought to be associated with lung cancer. The incidence of clubbing fingers in lung cancer is about 10-29%, and it is more associated with non-small cell lung cancer than small cell lung cancer. We present a rare case of pulmonary primitive neuroectodermal tumor with clubbing fingers. A 56-year-old man had suffered from progressive dyspnea on exertion, accompanied with cough, abdominal fullness and body weight loss of 10 kg in the most recent 5 months. On examination, obvious digital clubbing was found in both hands. Imaging study demonstrated a huge left lung tumor. Sonography-guided biopsy was performed and the pathology report suggested primitive neuroectodermal tumor. The patient received chemotherapy with doxorubicin, decarbazine and ifosfamide, and began gradually feeling less dyspneic after chemotherapy.

並列關鍵字

nail ； lung tumor ； hypertrophic osteoarthropathy

國際替代計量

Pulmonary Primitive Neuroectodermal Tumor Associated with Digital Clubbing-A Case Report

全文下載

主題瀏覽