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Gastrointestinal Metastasis of Primary Lung Mucoepidermoid Carcinoma: A Case Report

原發性肺部黏液表皮樣癌合併腸胃道轉移:病例報告

摘要


肺癌是一常見之腫瘤且常常會有其他器官之轉移,如肺臟、肝臟及腎上腺。然而,肺癌產生腸胃道之轉移仍然相當少見。而當肺癌產生腸胃道之轉移時,常常是沒有症狀的,如果有產生症狀,最常見的則是腸胃道出血、腹痛,腸阻塞及腸穿孔。而最常產生小腸轉移的原發性肺癌是肺腺癌。當肺癌合併腸胃道轉移時,通常代表著相當不好的預後。我們在這一邊提出一個80歲的男性病患,他本身是粘液表皮樣肺癌合併肺臟及縱膈腔淋巴結轉移之第四期肺癌患者。此患者突然產生急性腹痛,經電腦斷層檢查診斷為腹部中空器官破裂。經緊急剖腹手術發覺為回腸穿孔,手術取下之標本證實此為原發性肺部腫瘤合併腸胃道轉移所致。然而此病患在手術後約兩周後還是不治死亡。

並列摘要


Primary lung cancer is a common neoplasm, and frequently metastasizes to internal organs such as the lung, liver and adrenal gland; however, it is relatively rare for lung cancer to metastasize to the gastrointestinal tract. The common symptoms are gastrointestinal bleeding, abdominal pain, obstruction, and perforation. The most common histology of small intestinal metastasis from lung cancer is adenocarcinoma. Gastrointestinal tract metastasis is an extremely poor prognostic indicator of lung carcinoma. We described an 80-year-old male with mucoepidermoid carcinoma of the lung, left lower lobe, with mediastinal lymphadenopathy and lung-to-lung metastases, cT2N2M1, stage IV status post-chemotherapy who suffered from an acute onset of abdominal pain. The abdominal CT revealed a suspected ruptured hollow organ. Emergency laparotomy revealed ileum perforation, and the pathology of the surgical specimen proved intestinal metastasis from lung cancer. The patient expired about 2 weeks after the laparotomy.

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