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Inflammatory Pseudotumor of the Lungs and Mediastinum: Two Case Reports

肺部與縱膈腔發炎性假性腫瘤:兩個病例報告

摘要


肺部及縱膈腔的發炎性假性腫瘤是相當罕見的疾病,但當我們在面對原發性胸腔腫瘤時,還是要將其列入鑑別診斷。它的臨床表現可以是良性,也可以是惡性。診斷常常要等到手術切除後才能確定。隨著免疫染色法的進步,我們可以利用間變性淋巴瘤激酶以及免疫球蛋白G4染色來幫助我們做鑑別診斷。我們報告2個發炎性假性腫瘤的病例,分別接受類固醇和手術治療。發炎性假性腫瘤的病理學、命名學、影像表現及臨床表現將一併討論。

並列摘要


Inflammatory pseudotumor (IPT) of the lungs and the mediastinum is rare, but should be considered when dealing with primary pulmonary tumors. In terms of pathology, it is composed of fibroblastic and myofibroblastic proliferations and inflammatory cells. Its clinical behavior varies widely, ranging from a benign evolution to a possible malignancy. Diagnosis is very difficult and often only after tumor resection. With the advances in immunohistochemistry, anaplastic lymphoma kinase (ALK) and immunoglobulin G4 (IgG4) staining can now provide better answers. We report 2 cases of IPT with different pathologic features that were treated with steroid therapy and surgical resection, respectively. The pathogenesis, terminology, clinical behavior, and imaging of pulmonary IPT are briefly examined.

並列關鍵字

inflammatory pseudotumor

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