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Marantic Endocarditis in a Patient with Lung Cancer: Report of a Case and Review of the Literature

肺癌合併marantic心內膜炎:案例報告及文獻回顧

摘要


marantic心內膜炎,也被稱為非細菌性血栓性心內膜炎,是一種在晚期癌症不常見的併發症。這個疾病主要特徵是在心臟瓣膜上黏附因高凝血功能造成之非感染性血栓,進而造成全身性廣泛的栓塞。在這篇病例報告中,我們描述一位患有非小細胞肺腺癌的52歲女性,在腦部與四肢出現廣泛性的缺血性栓塞。根據臨床表徵與心臟超音波結果,最後診斷為非細菌性血栓性心內膜炎。我們同時進行此特殊疾病的文獻回顧。

並列摘要


Marantic endocarditis, also known as nonbacterial thrombotic endocarditis (NBTE), is an uncommon complication of advanced malignancy. The disease is characterized by hypercoagulability-related non-infective thrombi on valvular leaflets causing extensive embolization. In this report, we describe a 52-year-old woman with lung adenocarcinoma who developed extensive embolic infarction of the brain and extremities. Nonbacterial thrombotic endocarditis was diagnosed based on the clinical presentation and results from echocardiography. We also review the related literature concerning this rare disease entity.

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