Primary Pulmonary Synovial Sarcoma: A Case Report and Literature Review

原發性肺滑膜肉瘤：病例報告

賴寶民(Pao-Min Lai) ； 李仁智(Jen-Jyh Lee) ； 張恩庭(En-Tin Chang) ； 許永祥(Yung-Hsiang Hsu) ； 林智斌(Chih-Bin Lin)

《胸腔醫學》 29卷6期 (2014/12) Pp. 344-350

摘要

原發性滑膜肉瘤在肺部是相當罕見的腫瘤，我們報導了一位59歲女性，因為胸悶及活動性呼吸喘及咳血來求診，胸部CXR及電腦斷層顯示腫瘤位於右下肺，經手術切除之後病理報告為單相滑膜肉瘤，且確診為滑膜肉瘤SYT-SSX第二型。術後七個月胸部電腦斷層發現腫瘤局部復發，但病人拒絕進一步治療與追蹤，病人於兩個月之後死於敗血性休克。

關鍵字

肺腫瘤 ； 滑膜肉瘤

並列摘要

Primary synovial sarcoma in the lung is a very rare disease. Herein, we presented a 59-year-old female with the symptoms of chest tightness, exertional dyspnea and hemoptysis. CXR and chest CT showed a primary tumor located at the right lower lobe with invasion into the right middle lobe. Curative operation with bilobectomy was performed and monophasic synovial sarcoma was suspected by histology and immunohistochemical stains. The tumor was then confirmed by reverse transcription-PCR analysis to be a SYT-SSX2 fusion type. After 7 months of follow-up, local recurrence was noted. The patient was lost to follow-up thereafter and died 2 months later due to sepsis.

並列關鍵字

lung tumor ； synovial sarcoma ； SYT-SSX fusion type