- 期刊
Primary Pulmonary Mesenchymal Chondrosarcoma: A Case Report with Clinical Course and Response to Radiation
原發性肺臟間葉軟骨肉瘤：一例臨床病程及放射治療反應之案例報告
摘要
原發性肺臟軟骨肉瘤是一種罕見的惡性腫瘤。原發性間葉軟骨肉瘤是其中的一個亞型，它有由分化的軟骨混合著未分化的小圓細胞所組成的固體高度細胞性區域的特徵，肺臟原發性間葉軟骨肉瘤是一種極為罕見的惡性腫瘤。就我們所知，目前僅有4例的英文案例報告。然而，這種高度局部復發及遠處轉移的惡性腫瘤，在過去的案例報告中並沒有術後的正子電腦斷層掃描以證明肺臟為原發。除此之外，完整的臨床病程、以及如同此位病人因腫瘤復發合併呼吸道壓迫瀕臨呼吸衰竭，我們以放射治療作為營救治療與症狀緩解的工具，成功讓病人脫離氣管插管的風險，此臨床反應在過去也未被提及的。因此，我們追蹤了這位病患有37個月，並且記錄了這位原發性肺臟間葉軟骨肉瘤的臨床病程。
並列摘要
Primary chondrosarcoma of the lung is a rare malignancy. Primary mesenchymal chondrosarcoma, a subtype of chondrosarcoma characterized by differentiated cartilage admixed with solid highly cellular areas composed of undifferentiated small round cells, is an extremely rare primary malignancy of lung origin. To the best of our knowledge, only 4 cases of primary pulmonary mesenchymal chondrosarcoma have been reported in the English literature. However, in past published cases of this malignancy, with its high local relapse rate and distant metastasis, there was no report of postoperative positron emission tomographycomputed tomography (PET-CT) scans that could prove the primary origin was the lung. In addition, the clinical course and response to radiation as rescue therapy were not discussed before. We followed up our patient for 37 months and report the case.
延伸閱讀
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